Math in Medicine: A Real-World Application
Created byAnge Evans
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Math in Medicine: A Real-World Application

Grade 11MathScience1 days
This project explores the integration of mathematical principles into medical practices, focusing on applying concepts like half-life, Newton's Law of Cooling, unit conversions, and significant figures to optimize medical treatments and ensure accuracy in medical decision-making. Students engage with real-world medical scenarios, such as calculating drug dosages, estimating time of death using body temperature, and converting vital signs, enhancing their problem-solving skills and interdisciplinary understanding. The project culminates in integrating these mathematical principles to solve comprehensive medical scenarios, promoting a deeper understanding of the interdisciplinary nature of math and medicine. Students reflect on their learning, the challenges they faced, and the enhancement of their problem-solving skills.
Half-LifeNewton's Law of CoolingUnit ConversionsSignificant FiguresMedical ScenariosVital SignsDrug Dosage
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Inquiry Framework

Question Framework

Driving Question

The overarching question that guides the entire project.In what ways can mathematical principles, such as half-life, Newton's Law of Cooling, and unit conversions, be integrated with the interpretation of vital signs to optimize medical treatments and ensure accuracy in medical decision-making?

Essential Questions

Supporting questions that break down major concepts.
  • How can mathematical models be used to describe and predict changes in medical contexts?
  • How do different units of measurement impact calculations and interpretations in medicine?
  • How does the half-life formula relate to medical treatments and drug dosages?
  • How can Newton's Law of Cooling be applied to understanding changes in body temperature?
  • How do significant figures affect the accuracy and reliability of medical calculations?
  • How are vital signs measured, interpreted, and used in medical decision-making?

Standards & Learning Goals

Learning Goals

By the end of this project, students will be able to:
  • Apply the half-life formula to calculate drug dosages and predict medication concentrations over time.
  • Apply Newton's Law of Cooling to model changes in body temperature in medical scenarios.
  • Perform unit conversions accurately to ensure consistency and precision in medical calculations.
  • Apply the rules of significant figures to ensure accuracy and reliability in medical data and calculations.
  • Interpret and convert vital signs (e.g., temperature, pulse rate, blood pressure) to inform medical decisions.

Entry Events

Events that will be used to introduce the project to students

Vital Signs Forensics

Students are presented with a fictional crime scene scenario where the victim's vital signs were recorded at the time of death. Using Newton's Law of Cooling, half-life of potential toxins, and accurate unit conversions, students must work backward to estimate the time of death and identify potential causes, blending forensic science with mathematical modeling.

Contaminated Cooling System Challenge

The school's cooling system has been contaminated with a radioactive substance. Students receive data on the substance's half-life, contamination levels, and the system's cooling rate. They must use math and science principles to determine the risk and devise a decontamination plan, connecting math to a relevant and timely issue.
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Portfolio Activities

Portfolio Activities

These activities progressively build towards your learning goals, with each submission contributing to the student's final portfolio.
Activity 1

Vital Signs Conversion Station

Students will begin by mastering the essential skill of converting vital signs between different units of measurement. This foundational activity ensures students can accurately interpret and utilize vital signs data in various medical contexts.

Steps

Here is some basic scaffolding to help students complete the activity.
1. Research common vital signs (temperature, pulse rate, blood pressure) and their standard units of measurement (e.g., Celsius and Fahrenheit for temperature, beats per minute for pulse rate, mmHg for blood pressure).
2. Find the conversion formulas or factors for converting between these units (e.g., °C to °F, bpm to beats per second).
3. Complete a worksheet with a series of conversion problems, starting with simple conversions and progressing to more complex, multi-step conversions.

Final Product

What students will submit as the final product of the activityA completed worksheet demonstrating accurate conversions of vital signs between different units of measurement.

Alignment

How this activity aligns with the learning objectives & standardsAddresses the learning goal: Perform unit conversions accurately to ensure consistency and precision in medical calculations.
Activity 2

Significant Figures in Medical Data

This activity focuses on the application of significant figures in medical measurements and calculations. Students will learn how to determine the number of significant figures in a measurement and how to apply this knowledge in calculations to maintain accuracy and reliability.

Steps

Here is some basic scaffolding to help students complete the activity.
1. Learn the rules for determining significant figures in measurements (e.g., non-zero digits are always significant, zeros between non-zero digits are significant).
2. Practice identifying the number of significant figures in a set of medical data (e.g., temperature readings, blood pressure measurements, drug dosages).
3. Perform calculations (addition, subtraction, multiplication, division) with medical data, applying the rules for significant figures to round the final answer correctly.

Final Product

What students will submit as the final product of the activityA set of correctly calculated medical data, with all answers rounded to the appropriate number of significant figures.

Alignment

How this activity aligns with the learning objectives & standardsAddresses the learning goal: Apply the rules of significant figures to ensure accuracy and reliability in medical data and calculations.
Activity 3

Half-Life Dosage Calculations

Students will apply the half-life formula to calculate drug dosages and predict medication concentrations over time. This activity will help students understand how medications decay in the body and how to determine appropriate dosing intervals.

Steps

Here is some basic scaffolding to help students complete the activity.
1. Understand the concept of half-life and its application in drug metabolism.
2. Learn the half-life formula: N(t) = N0 * (1/2)^(t/T), where N(t) is the amount remaining after time t, N0 is the initial amount, and T is the half-life.
3. Solve a series of problems involving drug dosages, half-lives, and medication concentrations. Calculate the amount of drug remaining after a certain time, determine the half-life of a drug given its initial and final concentrations, and calculate appropriate dosing intervals to maintain therapeutic levels.

Final Product

What students will submit as the final product of the activityA set of solved problems demonstrating the correct application of the half-life formula in drug dosage calculations.

Alignment

How this activity aligns with the learning objectives & standardsAddresses the learning goal: Apply the half-life formula to calculate drug dosages and predict medication concentrations over time.
Activity 4

Newton's Law of Cooling and Body Temperature

This activity explores Newton's Law of Cooling and its applications in medical scenarios, particularly in estimating time of death or monitoring patient temperature changes. Students will use mathematical models to understand how body temperature changes over time.

Steps

Here is some basic scaffolding to help students complete the activity.
1. Understand Newton's Law of Cooling: dT/dt = -k(T - Ts), where dT/dt is the rate of change of temperature, T is the object's temperature, Ts is the surrounding temperature, and k is a constant.
2. Solve problems involving body temperature changes, time of death estimation, and cooling rates. Use the formula to calculate the time it takes for a body to cool to a certain temperature, determine the surrounding temperature given the body temperature and cooling rate, and calculate the cooling constant k.
3. Discuss the limitations and assumptions of Newton's Law of Cooling in real-world medical scenarios.

Final Product

What students will submit as the final product of the activityA written analysis of body temperature problems using Newton's Law of Cooling, including calculations and a discussion of the law's limitations.

Alignment

How this activity aligns with the learning objectives & standardsAddresses the learning goal: Apply Newton's Law of Cooling to model changes in body temperature in medical scenarios.
Activity 5

Integrating Math in Medical Scenarios

In this final activity, students will integrate all the mathematical principles learned (unit conversions, significant figures, half-life formula, and Newton's Law of Cooling) to solve comprehensive medical scenarios. This activity aims to enhance their problem-solving skills and deepen their understanding of the interdisciplinary nature of math and medicine.

Steps

Here is some basic scaffolding to help students complete the activity.
1. Present students with complex medical scenarios that require the integration of unit conversions, significant figures, half-life formula, and Newton's Law of Cooling (e.g., a patient with a fever requires a specific drug dosage, and students must calculate the correct dosage considering the drug's half-life and the patient's body temperature).
2. Work in groups to analyze the medical scenarios, identify the relevant mathematical principles, and develop a step-by-step solution.
3. Present their solutions to the class, explaining their reasoning, calculations, and assumptions.

Final Product

What students will submit as the final product of the activityA detailed written report of the analysis of the medical scenarios, including all calculations, reasoning, and assumptions.

Alignment

How this activity aligns with the learning objectives & standardsAddresses all learning goals: Apply the half-life formula, Apply Newton's Law of Cooling, Perform unit conversions accurately, Apply the rules of significant figures, and Interpret and convert vital signs.
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Rubric & Reflection

Portfolio Rubric

Grading criteria for assessing the overall project portfolio

Math in Medicine Portfolio Rubric

Category 1

Unit Conversions

Accuracy and proficiency in converting between different units of measurement for vital signs and other medical data.
Criterion 1

Conversion Accuracy

The degree to which unit conversions are performed correctly and consistently.

Exemplary
4 Points

All unit conversions are performed accurately and efficiently, demonstrating a deep understanding of unit relationships.

Proficient
3 Points

Most unit conversions are performed accurately, with only minor errors or inconsistencies.

Developing
2 Points

Some unit conversions are performed accurately, but there are noticeable errors and inconsistencies.

Beginning
1 Points

Unit conversions are largely inaccurate or incomplete, indicating a limited understanding of unit relationships.

Criterion 2

Problem-Solving Application

Effectiveness in applying unit conversions to solve practical medical problems.

Exemplary
4 Points

Demonstrates sophisticated problem-solving skills by accurately applying unit conversions to complex medical scenarios.

Proficient
3 Points

Effectively applies unit conversions to solve most medical problems, with a clear understanding of the context.

Developing
2 Points

Applies unit conversions to solve some medical problems, but struggles with more complex scenarios.

Beginning
1 Points

Struggles to apply unit conversions to solve medical problems, indicating a lack of understanding of the practical application.

Category 2

Significant Figures

Proper application of significant figures in medical measurements and calculations.
Criterion 1

Identification and Application

Correctly identifies and applies the rules of significant figures in medical data and calculations.

Exemplary
4 Points

Consistently and accurately identifies and applies the rules of significant figures in all medical data and calculations, demonstrating a comprehensive understanding.

Proficient
3 Points

Identifies and applies the rules of significant figures correctly in most medical data and calculations, with only minor errors.

Developing
2 Points

Shows some understanding of significant figures but makes errors in identification or application in medical data and calculations.

Beginning
1 Points

Struggles to identify and apply the rules of significant figures in medical data and calculations, indicating a limited understanding.

Criterion 2

Accuracy in Calculations

Maintains accuracy in calculations by correctly rounding answers based on significant figures.

Exemplary
4 Points

Maintains exceptional accuracy in calculations by consistently rounding answers to the appropriate number of significant figures.

Proficient
3 Points

Maintains accuracy in most calculations by rounding answers to the appropriate number of significant figures, with only minor inconsistencies.

Developing
2 Points

Shows some accuracy in calculations but makes errors in rounding answers based on significant figures.

Beginning
1 Points

Struggles to maintain accuracy in calculations due to errors in rounding answers based on significant figures.

Category 3

Half-Life Dosage

Accurate application of the half-life formula to calculate drug dosages and predict medication concentrations.
Criterion 1

Formula Application

Correctly applies the half-life formula to solve problems related to drug dosages and medication concentrations.

Exemplary
4 Points

Consistently and accurately applies the half-life formula to solve complex problems, demonstrating a thorough understanding of drug metabolism.

Proficient
3 Points

Applies the half-life formula correctly to solve most problems related to drug dosages and medication concentrations, with only minor errors.

Developing
2 Points

Shows some understanding of the half-life formula but makes errors in application or calculations.

Beginning
1 Points

Struggles to apply the half-life formula, indicating a limited understanding of its use in drug dosage calculations.

Criterion 2

Dosage Calculation Accuracy

Calculates drug dosages accurately using the half-life formula and relevant medical information.

Exemplary
4 Points

Calculates drug dosages with exceptional accuracy, demonstrating a clear understanding of the factors influencing medication concentrations.

Proficient
3 Points

Calculates drug dosages accurately in most cases, with only minor discrepancies or errors.

Developing
2 Points

Shows some accuracy in dosage calculations but makes errors that could impact patient safety.

Beginning
1 Points

Struggles to calculate drug dosages accurately, indicating a significant lack of understanding of the relevant factors.

Category 4

Newton's Law of Cooling

Application of Newton's Law of Cooling to model changes in body temperature in medical scenarios.
Criterion 1

Formula Comprehension

Understands and correctly applies Newton's Law of Cooling in medical contexts.

Exemplary
4 Points

Demonstrates a comprehensive understanding of Newton's Law of Cooling and its applications, including its limitations in real-world scenarios.

Proficient
3 Points

Applies Newton's Law of Cooling correctly in most medical scenarios, with a clear understanding of the formula and its components.

Developing
2 Points

Shows some understanding of Newton's Law of Cooling but struggles with application or interpretation.

Beginning
1 Points

Demonstrates a limited understanding of Newton's Law of Cooling and its relevance in medical contexts.

Criterion 2

Problem Analysis

Effectively analyzes problems and provides accurate solutions using Newton's Law of Cooling.

Exemplary
4 Points

Provides insightful analysis and accurate solutions to complex problems using Newton's Law of Cooling, demonstrating a strong grasp of the underlying principles.

Proficient
3 Points

Analyzes problems effectively and provides accurate solutions using Newton's Law of Cooling in most cases.

Developing
2 Points

Attempts to analyze problems using Newton's Law of Cooling but struggles to provide accurate solutions.

Beginning
1 Points

Struggles to analyze problems or provide solutions using Newton's Law of Cooling, indicating a limited understanding.

Category 5

Integration and Application

Ability to integrate multiple mathematical principles to solve complex medical scenarios.
Criterion 1

Problem-Solving

Effectively integrates unit conversions, significant figures, half-life, and Newton's Law of Cooling to solve complex medical scenarios.

Exemplary
4 Points

Demonstrates exceptional problem-solving skills by seamlessly integrating all mathematical principles to provide comprehensive and accurate solutions to complex medical scenarios.

Proficient
3 Points

Integrates most mathematical principles effectively to solve medical scenarios, with a clear and logical approach.

Developing
2 Points

Shows some ability to integrate mathematical principles but struggles with complex medical scenarios.

Beginning
1 Points

Struggles to integrate mathematical principles to solve medical scenarios, indicating a limited understanding of the interdisciplinary nature of the problems.

Criterion 2

Reasoning and Assumptions

Provides clear reasoning and justifies assumptions made in solving medical scenarios.

Exemplary
4 Points

Provides clear, logical reasoning and thoroughly justifies all assumptions made in solving medical scenarios, demonstrating a sophisticated understanding of the underlying principles.

Proficient
3 Points

Provides clear reasoning and justifies most assumptions made in solving medical scenarios.

Developing
2 Points

Shows some reasoning but struggles to justify assumptions or provide clear explanations.

Beginning
1 Points

Struggles to provide reasoning or justify assumptions made in solving medical scenarios, indicating a limited understanding of the problem-solving process.

Reflection Prompts

End-of-project reflection questions to get students to think about their learning
Question 1

How did your understanding of the relationship between mathematical principles and medical practices evolve throughout this project?

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Question 2

Which of the mathematical concepts (half-life, Newton's Law of Cooling, unit conversions, significant figures) did you find most challenging to apply in the medical context, and why?

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Question 3

In what ways did the 'Integrating Math in Medical Scenarios' activity enhance your problem-solving skills and interdisciplinary understanding? Provide specific examples.

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Question 4

How confident are you in your ability to accurately perform medical calculations involving unit conversions, significant figures, and the half-life formula?

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Question 5

To what extent do you agree that mathematical modeling is essential for making informed decisions in medical treatments and diagnostics?

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Question 6

Which activity (Vital Signs Conversion Station, Significant Figures in Medical Data, Half-Life Dosage Calculations, Newton's Law of Cooling and Body Temperature, Integrating Math in Medical Scenarios) did you find the most engaging and helpful for your learning? Explain why.

Multiple choice
Required
Options
Vital Signs Conversion Station
Significant Figures in Medical Data
Half-Life Dosage Calculations
Newton's Law of Cooling and Body Temperature
Integrating Math in Medical Scenarios